NDM-1 K. pneumoniae identified in 9 patients in Toronto hospital

January 6, 2013

HAIs in the News:  Healio Infectious Disease News, doctor January 2, 2013

Helio Infectious Disease reports on research presented in Infection Control and Hospital Epidemiology about NDM-1 Klebsiella pneumonia identified in patients of a Toronto hospital.

Two distinct clones of New Delhi Metallo-?-Lactamase-1-Producing Klebsiella pneumoniae were identified at a tertiary care center in Toronto, researchers reported in Infection Control and Hospital Epidemiology.

Nine patients with NDM-1 K. pneumoniae were identified from January 2011 to March 2012. Pulsed-field gel electrophoresis (PFGE) showed that there were two different clones. For one clone, the index patient had recently received health care in India. The index patient for the second clone had no previous travel to India. Both clones were resistant to beta-lactams, fluoroquinolones, aminoglycosides and trimethoprim-sulfamethoxazole.

“The major take-home message is that the epidemiology of antibiotic-resistant organisms continues to evolve,” Andrew Simor, MD, of Sunnybrook Health Sciences Center in Toronto, told Infectious Disease News. “With regards to carbapenem-resistance associated with NDM-1, this should no longer be considered merely related to medical tourism, as initially described. “We need to acknowledge that gram-negative bacteria carrying this resistance determinant may be acquired and transmitted in health care settings in North America and globally.”

Source: Healio Infectious Disease News

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