Study of Trauma Patients Reveals Clinical Impact and Economic Burden of HAIs

July 18, 2011

A study published in the July issue of Archives of Surgery reveals that trauma patients with hospital-acquired infections (HAIs) have an increased risk for mortality, and longer lengths of stay, vcialis 40mg and incur higher inpatient costs.

The retrospective study utilized the Healthcare Cost and Utilization Project Nationwide Inpatient Sample to “explore the clinical impact and economic burden of” HAIs for trauma patients.

Researchers reviewed the association between HAIs and in-hospital mortality, length of stay, and inpatient costs.  HAIs examined were sepsis, pneumonia, Staphylococcus infections, and Clostridium difficile-associated disease (CDAD).  Logistic regression and generalized linear models were used to analyze the results.

The researchers found that trauma patients with HAIs had significantly higher mortality, cost, and length of stay compared to patients who did not experience a HAI.

Patients suffering from sepsis were approximately 6 times more likely to die compared with patients without a HAI.  Patients with other types of HAIs had 1.5- to 1.9-fold higher odds of mortality compared to the controls.

Patients experiencing HAIs had costs approximately 2 to 2.5 times higher than those without HAIs.

Length of stay was also higher.  The median length of stay for patients with HAIs was approximately 2-fold higher than those without HAIs.

Reference:  Glance LG, Stone, PW, Mukamel DB, and Dick AW.  Increases in Mortality, Length of Stay, and Cost Associated With Hospital-Acquired Infections in Trauma Patients.  Archives of Surgery, 146(7): 794-801 (July 2011).

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